In plain English
Pinealon is one of the shortest peptides used: just three amino acids. It was developed in Russia as a bioregulator for the brain, to support nerve cells under stress and with age.
What it's used for
- Memory and mental clarity
- Brain aging
- Sleep and body-clock support
- Recovery after brain stress
Benefits
In animal and cell studies, pinealon protected nerve cells from oxidative stress and lack of oxygen, and small Russian human studies reported improved memory and well-being in older adults. Users report clearer thinking and better sleep.
How it works
In simple terms: it is thought to help brain cells handle stress and switch on protective genes.
Its tiny size may let it enter cells and the nucleus, where it is thought to influence gene activity linked to antioxidant defense and cell survival.
Development history
- 2000s: Developed at the St. Petersburg Institute of Bioregulation and Gerontology under Vladimir Khavinson.
Typical protocols
Doses vary; these ranges are what users commonly report.
| Use | Dose | Frequency | Length |
|---|---|---|---|
| Brain support | 1–3 mg | Daily | 10–20 days |
Cycling
Short courses repeated a few times a year, typical of bioregulators.
Administration options
Subcutaneous injection or nasal spray.
Reconstitution and dosing calculator
Usually comes in 5 mg, 10 mg or 20 mg vials, mixed with 2 mL of bacteriostatic water.
Draw your syringe to
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Show the math
This tool does arithmetic only. It does not choose a dose or confirm that any substance is right for you. Double-check every result against your syringe and your clinician’s instructions.
Side effects and safety
- Users report it is generally well tolerated.
- Very little safety data in people.
- Avoid during pregnancy and breastfeeding.
Common stacks
- Epitalon: for sleep and longevity.
- Cortexin or Cerebrolysin: other brain-support peptides.
Storage
Powder: refrigerate or freeze. After mixing: refrigerate at 2–8 °C and use within about 3 weeks.
Compare with
- Epitalon: pineal bioregulator aimed at sleep and aging.
- Semax: a stimulating nasal brain peptide.
Frequently asked questions
Is Pinealon made from the pineal gland?
No. Despite the name, it is a synthetic three-amino-acid peptide aimed at the brain in general.
References
- Khavinson V, et al. Pinealon increases cell viability by suppression of free radical levels and activating proliferative processes. Rejuvenation Res. 2011;14(5):535-541.